- TBD at Dallas Stars: Western Conference Second Round (Home Game 1, If Necessary)at American Airlines Center
- Missouri Tigers at South Carolina Gamecocks Softballat Carolina Softball Stadium at Beckham Field
- Toledo Mud Hens at Columbus Clippersat Huntington Park
- Sugar Land Space Cowboys at El Paso Chihuahuasat Southwest University Park
- Round Rock Express at Albuquerque Isotopesat Rio Grande Credit Union Field at Isotopes Park - Complex
- Omaha Storm Chasers at Iowa Cubsat Principal Park
- Durham Bulls at Gwinnett Stripersat Coolray Field
- Quad Cities River Bandits at Beloit Sky Carpat ABC Supply Stadium
- Texas A&M Aggies at LSU Tigers Baseballat Alex Box Stadium
- Tacoma Rainiers at Sacramento River Catsat Sutter Health Park
- Reno Aces at Las Vegas Aviatorsat Las Vegas Ballpark
- Salt Lake Bees at Oklahoma City Dodgersat Chickasaw Bricktown Ballpark
- Louisville Bats at St. Paul Saintsat CHS Field
- Vanderbilt Commodores at Georgia Bulldogs Baseballat Foley Field
- Ole Miss Rebels at Arkansas Lady Razorbacks Softballat Bogle Park
- Kentucky Wildcats at Tennessee Lady Volunteers Softballat Sherri Parker Lee Stadium
- Memphis Redbirds at Charlotte Knightsat Truist Field - Charlotte (formerly BB&T Ballpark)
- Tampa Tarpons at Dunedin Blue Jaysat TD Ballpark
- York Revolution at High Point Rockersat Truist Point
- Gastonia Honey Hunters at Charleston Dirty Birds Baseballat GoMart Ballpark (Formerly Appalachian Power Park)
- Stanford Cardinal at Arizona Wildcats Baseballat Hi Corbett Field
- Arkansas Razorbacks at Kentucky Wildcats Baseballat Kentucky Proud Park
- Long Island Ducks at Hagerstown Flying Boxcarsat Hagerstown Multi-Use Sports and Events Facility
- Ole Miss Rebels at Auburn Tigers Baseballat Plainsman Park
- TBD at Boston Bruins: Eastern Conference Second Round (Home Game 1, If Necessary)at TD Garden
- TBD at New Jersey Devils: Eastern Conference Second Round (Home Game 1, If Necessary)at Prudential Center
- Texas A&M Aggies at Florida Gators Softballat Katie Seashole Pressly Softball Stadium
- Frozenat Moran Theater at Jacksonville Center for the Performing Arts - Complex
- TBD at Carolina Hurricanes: Eastern Conference Second Round (Home Game 1, If Necessary)at PNC Arena
- TBD at New York Rangers: Eastern Conference Second Round (Home Game 1, If Necessary)at Madison Square Garden